Titrate the dosage of acetaminophen and codeine phosphate tablets slowly in geriatric individuals and usually reevaluate the client for indications of central anxious procedure despair (see WARNINGS).
Infants born to mothers physically dependent on opioids will also be physically dependent and will show respiratory issues and withdrawal indicators (see PRECAUTIONS, Pregnancy).
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When having acetaminophen and codeine phosphate tablets: Will not adjust your dose. Get acetaminophen and codeine phosphate tablets exactly as prescribed by your Health care supplier. Use the lowest dose possible for that shortest time necessary. For acute (short-time period) soreness, you could only ought to choose acetaminophen and codeine phosphate tablets for a couple of days.
Similarly there was no proof of carcinogenicity action in male and female mice at dietary doses up to four hundred mg/kg/working day of codeine sulfate (roughly five instances the maximum advised every day dose of 360 mg/working day for Grown ups with a mg/m2 basis) for 2 a long time.
Since aged patients are more likely to have lessened renal perform, care ought to be taken in dose assortment, and it could be beneficial to observe renal function.
Right before taking this product, notify more info your physician or pharmacist When you are allergic to acetaminophen or codeine; or to other opioid ache remedies (for example morphine); or if you have any other allergic reactions.
Proper evaluation on the individual, correct prescribing tactics, periodic reevaluation of therapy, and good dispensing and storage are read more correct steps that aid to limit abuse of opioid prescription drugs.
To reduce the chance of respiratory depression, suitable website dosing and titration of acetaminophen and codeine phosphate tablets are essential (see DOSAGE AND ADMINISTRATION).
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Doses increased than 60 mg have not been shown to further improve suffering reduction and therefore are connected with an increased incidence of adverse effects.
Acetaminophen and codeine phosphate tablets should not be utilized for an prolonged period of time Except if the suffering remains significant ample to involve an opioid analgesic and for which alternate therapy selections continue for being insufficient.
Misuse and abuse of acetaminophen and codeine phosphate tablets boosts risk of overdose, which may bring on central nervous program and respiratory melancholy, hypotension, seizures, and Dying. The risk is increased with concurrent abuse of acetaminophen and codeine phosphate tablets with Liquor together with other CNS depressants.
Get crisis support or connect with 911 at once if you are taking a lot of acetaminophen and codeine phosphate tablets (overdose). Any time you initially start out getting acetaminophen and codeine phosphate tablets, Whenever your dose is transformed, or if you take too much (overdose), serious or life-threatening respiration troubles that can cause Loss of life might happen.